Background: Toll-like receptors (TLRs) detect diverse pathogen-associated molecular patterns and play a critical role in the innate immune response.Hosts should activate TLR-signaling pathways to eliminate invading pathogens.However, excessive activation of these pathways may interrupt immune homeostasis, leading to several diseases.Therefore preci
Zygotic gene activation (ZGA) and epigenetic reprogramming are critical in early embryonic development in mammals, and transcription factors are involved in regulating these events.However, the effects of ELF4 on porcine embryonic development remain unclear.In High Temperature Oil this study, the expression of ELF4 was detected in early porcine emb
The importance of the Dutch Revolution of the late eighteenth century for political developments in the Northern Netherlands is still contested.Most historians view the period as the starting point of a number of democratic institutions, including Ready Meals elections.Others have pointed out, however, that the nineteenth century shows a remarkable